Description

3,5-Difluoro-2-Methoxybenzamide is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals due to the unique electronic properties imparted by the fluorine substituents. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the difluoro-methoxy motif can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials to modify solubility and electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and reference standards.

Basic Information

Product Name	3,5-Difluoro-2-Methoxybenzamide
CAS No.	874804-09-8
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	2-Methoxy-3,5-difluorobenzamide; 3,5-Difluoro-2-methoxybenzoic acid amide; Benzamide, 3,5-difluoro-2-methoxy-; 874804-09-8; 3,5-Difluoro-o-anisamide; 2-Methoxy-3,5-difluorobenzoic acid amide
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-Methoxybenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can supply material compliant with cGMP standards for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.