Description

2-Amino-5-Bromo-3-Fluorobenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, bromo, and fluoro substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of its halogen and amino groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers where fluorine substitution enhances stability and performance.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Amino-5-Bromo-3-Fluorobenzoic Acid
CAS No.	874784-14-2
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.03 g/mol
Synonyms	5-Bromo-3-fluoroanthranilic acid; 2-Amino-5-bromo-3-fluorobenzoic acid; Benzoic acid, 2-amino-5-bromo-3-fluoro-; 5-Bromo-3-fluoro-2-aminobenzoic acid; 3-Fluoro-5-bromoanthranilic acid; 874784-14-2; 2-ABFA (abbreviation)
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.