Description

2,3-Difluoro-6-(Pivaloylamino)Benzoic Acid, also known as 5,6-Difluoro-n-Pivaloylanthranilic Acid, is a high-purity, multi-fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring both a protected amino group and a carboxylic acid functional group, which enables precise and efficient construction of complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients where the introduction of fluorine atoms is key to modulating biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoroanthranilic acid core can enhance product efficacy and environmental profile.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED devices, leveraging the electronic properties of the fluorinated aromatic system.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or as a scaffold for metal-organic frameworks (MOFs) in material science.
• Fluorinated Liquid Crystal Research: Acts as a building block for novel fluorinated mesogens in display technology applications.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in bespoke, multi-step synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2,3-Difluoro-6-(Pivaloylamino)Benzoic Acid
CAS No.	874784-13-1
Molecular Formula	C13H15F2NO3
Molecular Weight	271.26 g/mol
Synonyms	5,6-Difluoro-N-pivaloylanthranilic Acid; 5,6-Difluoro-2-[(2,2-dimethylpropanoyl)amino]benzoic Acid; 2-Amino-3,4-difluorobenzoic Acid Pivalamide; 2,3-Difluoro-6-[(2,2-dimethylpropanoyl)amino]benzoic Acid; N-(2-Carboxy-3,4-difluorophenyl)pivalamide; 874784-13-1; Pivaloyl-protected Difluoroanthranilic Acid
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-6-(Pivaloylamino)Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) that detail specifications and results for key parameters, including assay and impurity profiles. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for demanding applications in pharmaceutical development. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥98.5%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.