Description

6-Amino-3-Chloro-2-Fluoro-Benzoic Acid is a high-purity, multifunctional aromatic building block of significant commercial and research interest. This compound is valued for its unique substitution pattern, which makes it a versatile intermediate in advanced organic synthesis. It is primarily sought after by manufacturers and R&D teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology treatments.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated benzoic acid structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its functional groups.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Utilized in research laboratories for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	6-Amino-3-Chloro-2-Fluoro-Benzoic Acid
CAS No.	874782-54-4
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	2-Fluoro-3-chloro-6-aminobenzoic acid; 3-Chloro-2-fluoro-6-aminobenzoic acid; 6-Amino-3-chloro-2-fluorobenzoic acid; Benzoic acid, 6-amino-3-chloro-2-fluoro-; 2-Fluoro-6-amino-3-chlorobenzoic acid; 3-Chloro-6-amino-2-fluorobenzoic acid; 874782-54-4 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Chloro-2-Fluoro-Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and ensures traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.