Description

2-Amino-3-Bromo-5-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique trifluoromethoxy and bromo substituents make it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers where fluorine incorporation modifies material properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Amino-3-Bromo-5-(Trifluoromethoxy)Benzoic Acid
CAS No.	874774-41-1
Molecular Formula	C8H5BrF3NO3
Molecular Weight	300.03 g/mol
Synonyms	3-Bromo-2-amino-5-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-amino-3-bromo-5-(trifluoromethoxy)-; 2-Amino-3-bromo-5-(trifluoromethoxy)benzoic acid; 5-(Trifluoromethoxy)-2-amino-3-bromobenzoic acid; 3-Bromo-2-amino-α,α,α-trifluoro-p-cresotic acid; 2-Amino-3-bromo-5-trifluoromethoxybenzoic acid; 874774-41-1
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Bromo-5-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.