Description

3-Fluoro-5-Pyrrolidin-1-Ylbenzoic Acid is a high-purity fluorinated benzoic acid derivative featuring a pyrrolidine substituent, making it a valuable and versatile building block in advanced chemical synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily targeted at research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine atom and heterocyclic moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require specific fluorinated aromatic components.
• Chemical Biology Probes: Useful for creating fluorescent tags or molecular probes for studying biological processes due to its modifiable carboxylic acid group.

Basic Information

Product Name	3-Fluoro-5-Pyrrolidin-1-Ylbenzoic Acid
CAS No.	874133-18-3
Molecular Formula	C11H12FNO2
Molecular Weight	209.22 g/mol
Synonyms	3-Fluoro-5-(1-pyrrolidinyl)benzoic Acid; 5-(Pyrrolidin-1-yl)-3-fluorobenzoic Acid; Benzoic acid, 3-fluoro-5-(1-pyrrolidinyl)-; 874133-18-3; 3-Fluoro-5-pyrrolidin-1-yl-benzoic acid; 3-Fluoro-5-(pyrrolidin-1-yl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Pyrrolidin-1-Ylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.