Description

Tolterodine S-Enantiomer (15 Mg) ((S)-2-[3-(Diisopropylamino)-1-Phenylpropyl]-4-Methylphenol Tartrate) is the single, pharmacologically active enantiomer of the antimuscarinic agent Tolterodine, offered as a high-purity tartrate salt. This compound is critical for the development and production of enantiomerically pure active pharmaceutical ingredients (APIs) targeting overactive bladder syndrome. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in chiral drug synthesis, process development, and analytical method validation. The product is supplied with a guaranteed specification to ensure batch-to-batch consistency for your critical applications.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Direct use as the key chiral building block in the manufacture of enantiomerically pure Tolterodine and its finished dosage forms.
• Pharmaceutical R&D: Serving as a reference standard and starting material for novel drug development, metabolite studies, and chiral switching projects.
• Analytical Standard: Utilized as a primary standard for HPLC, LC-MS, and other chromatographic methods to assay drug products and ensure quality control.
• Process Chemistry: Employed in scaling up and optimizing chiral synthesis routes for commercial pharmaceutical production.
• Pharmacology Research: Used in *in-vitro* and *in-vivo* studies to investigate the specific pharmacological profile and receptor binding affinity of the (S)-enantiomer.
• Regulatory Submissions: Provides the necessary certified material for inclusion in Drug Master Files (DMFs), Investigational New Drug (IND), and New Drug Application (NDA) filings.

Basic Information

Item	Detail
Product Name	Tolterodine S-Enantiomer (15 Mg) ((S)-2-[3-(Diisopropylamino)-1-Phenylpropyl]-4-Methylphenol Tartrate)
CAS No.	873551-03-2
Molecular Formula	C26H37NO7
Molecular Weight	475.58 g/mol
Synonyms	(S)-Tolterodine Tartrate; (S)-Tolterodine L-Tartrate; (S)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-methylphenol (2R,3R)-2,3-dihydroxybutanedioate (1:1); (S)-Tolterodine Hydrogen Tartrate; Detrol S-Enantiomer; (S)-5-(2-Methyl-1-(3-(diisopropylamino)-1-phenylpropyl)phenol tartrate; PNU-200583 (Tartrate Salt)
EINECS	Contact for details

Quality Control

Every batch of our Tolterodine S-Enantiomer Tartrate is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing identity, purity, residual solvents, and related substances is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.5% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.