Description

Ethyl 2-Fluoro-4-Methylbenzoylformate is a high-purity, fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which incorporates both a reactive α-ketoester moiety and a strategically placed fluorine atom, enabling precise structural modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the fluorine atom can improve bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials and liquid crystals, where fluorinated aromatic systems are crucial.
• Chemical Biology Probes: Utilized as a building block for synthesizing fluorinated probes and tags used in studying biological mechanisms and drug-target interactions.

Basic Information

Product Name	Ethyl 2-Fluoro-4-Methylbenzoylformate
CAS No.	873547-99-0
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	Ethyl 2-Fluoro-4-methylbenzoylformate; Ethyl (2-Fluoro-4-methylphenyl)(oxo)acetate; 2-Fluoro-4-methylbenzoylformic Acid Ethyl Ester; α-Oxo-2-fluoro-4-methylbenzeneacetic Acid Ethyl Ester; Ethyl α-Oxo-2-fluoro-p-toluate; Ethyl 2-Fluoro-4-methyl-α-oxobenzeneacetate; Ethyl (2-Fluoro-4-methylbenzoyl)formate; 873547-99-0
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-4-Methylbenzoylformate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.