Description

Benzoic Acid, 2-Fluoro-5-(Methylsulfonyl)-, Methyl Ester is a high-value, fluorinated aromatic ester derivative, distinguished by its methylsulfonyl and fluorine substituents which confer unique electronic and steric properties. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, enabling the development of novel active ingredients. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of advanced electronic materials for displays and optoelectronic devices due to its specific aromatic structure.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions, Suzuki-Miyaura couplings, and as a ligand precursor in transition metal catalysis.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing properties like thermal stability, solubility, or reactivity for high-performance materials.
• Chemical Research (R&D): Utilized in academic and industrial laboratories for method development and the exploration of new chemical entities in medicinal and materials chemistry.

Basic Information

Product Name	Benzoic Acid, 2-Fluoro-5-(Methylsulfonyl)-, Methyl Ester
CAS No.	865663-98-5
Molecular Formula	C9H9FO4S
Molecular Weight	232.23 g/mol
Synonyms	Methyl 2-Fluoro-5-(methylsulfonyl)benzoate; 2-Fluoro-5-methanesulfonyl-benzoic Acid Methyl Ester; 5-(Methylsulfonyl)-2-fluorobenzoic Acid Methyl Ester; Methyl 5-(Methylsulfonyl)-2-fluorobenzoate; 2-Fluoro-5-methylsulfonyl Methyl Benzoate; 865663-98-5; Methyl 2-Fluoro-5-methylsulfonylbenzoate
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 2-Fluoro-5-(Methylsulfonyl)-, Methyl Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive applications like pharmaceutical synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support customer needs for regulatory filings and cGMP compliance where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.