Description

6-Fluoro-3-Methylbenzo[B]Thiophene-2-Carboxylic Acid is a high-purity, fluorinated heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceuticals and agrochemicals, where its unique benzo[b]thiophene core and fluorine substituent enable precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science: Serves as a monomer or functional unit in the research of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and scale-up projects.

Basic Information

Product Name	6-Fluoro-3-Methylbenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	863119-55-5
Molecular Formula	C10H7FO2S
Molecular Weight	210.22 g/mol
Synonyms	6-Fluoro-3-methyl-1-benzothiophene-2-carboxylic acid; 3-Methyl-6-fluorobenzo[b]thiophene-2-carboxylic acid; 2-Carboxy-6-fluoro-3-methylbenzo[b]thiophene; 863119-55-5; 6-Fluoro-3-methylbenzo[b]thiophene-2-carboxylic acid; 6-Fluoro-3-methyl-2-benzothiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-Methylbenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation, ensuring reliability for critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.