Description

1H-Imidazole-1-Acetic Acid, α-Fluoro is a high-value fluorinated imidazole derivative, a crucial building block in advanced organic synthesis. Its core value lies in its unique molecular structure, which incorporates both a reactive imidazole ring and a metabolically stable fluorine atom, making it indispensable for creating novel compounds with targeted properties. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients, as well as by fine chemical manufacturers producing specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Bioconjugation and Probe Development: Utilized in biochemical research for labeling and modifying biomolecules to create imaging probes or diagnostic tools.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of novel polymers and advanced functional materials.

Basic Information

Product Name	1H-Imidazole-1-Acetic Acid, α-Fluoro
CAS No.	861397-68-4
Molecular Formula	C5H5FN2O2
Molecular Weight	144.10 g/mol
Synonyms	2-Fluoro-2-(1H-imidazol-1-yl)acetic acid; (1H-Imidazol-1-yl)(fluoro)acetic acid; α-Fluoro-1H-imidazole-1-acetic acid; Fluoromethylimidazolylacetic acid; 1-Imidazolylfluoroacetic acid; 1-(Carboxyfluoromethyl)imidazole; 861397-68-4; FmImAA
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Acetic Acid, α-Fluoro is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.