Description

3-(1,3-Dioxolan-2-Yl)-4-Fluorobenzoicacid is a high-purity fluorinated benzoic acid derivative featuring a dioxolane-protected aldehyde or ketone functional group. This compound serves as a versatile and critical pharmaceutical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by R&D laboratories and manufacturing facilities in the pharmaceutical and agrochemical sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability and reactivity of the fluorobenzoate core.
• Organic Synthesis Reagent: Serves as a precursor for introducing the 4-fluorobenzoic acid moiety into more complex molecules in medicinal and process chemistry.
• Chemical Research: Valuable for academic and industrial research exploring new fluorination methodologies and heterocyclic compound libraries.
• Material Science Precursor: Potential use in the development of specialty polymers and liquid crystals where fluorine atoms enhance material properties.

Basic Information

Product Name	3-(1,3-Dioxolan-2-Yl)-4-Fluorobenzoicacid
CAS No.	852180-94-0
Molecular Formula	C10H9FO4
Molecular Weight	212.17 g/mol
Synonyms	4-Fluoro-3-(1,3-dioxolan-2-yl)benzoic acid; 3-(1,3-Dioxolan-2-yl)-4-fluorobenzoic acid; Benzoic acid, 4-fluoro-3-(1,3-dioxolan-2-yl)-; 852180-94-0; 4-Fluoro-3-(2',5'-dioxolanyl)benzoic acid; 3-(Dioxolan-2-yl)-4-fluorobenzoic acid; 4-Fluoro-3-(1,3-dioxolan-2-yl)benzoate
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxolan-2-Yl)-4-Fluorobenzoicacid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.