Description

(R)-Adx-47273 CAS NO 851881-59-9 is a high-purity chiral compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate or active pharmaceutical ingredient (API) for novel therapeutic agents targeting specific biological pathways. This compound is essential for research institutions and pharmaceutical companies engaged in the discovery and synthesis of new drugs, particularly in areas requiring enantiomerically pure substances.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used as a reference standard or a key scaffold in medicinal chemistry programs for hit-to-lead and lead optimization studies.
• Enantioselective Synthesis: Employed in the development of asymmetric synthesis routes to produce single-enantiomer drug candidates.
• Biochemical Research: Utilized as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Preclinical Development: Supports formulation studies and pharmacokinetic/pharmacodynamic (PK/PD) profiling during early-stage drug development.

Basic Information

Product Name	(R)-Adx-47273
CAS No.	851881-59-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ADX-47273 (R-enantiomer); (R)-ADX47273; (R)-ADX 47273; ADX47273, (R)-; (R)-4-[5-(4-Fluorophenyl)-2-methyl-4-thiazolyl]-1-methyl-1H-pyrazole; Potential research code names and IUPAC names may apply. Contact for a comprehensive list.
EINECS	Contact for details

Quality Control

Our (R)-Adx-47273 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by spectroscopic methods (IR, NMR, MS), and quantification of related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.