Description

Ethyl 3-Fluoro-5-Nitrobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and electron-deficient nature.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating chemical probes, tags, and linkers used in studying biological systems and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, fluorinated target molecules for clients.

Basic Information

Item	Detail
Product Name	Ethyl 3-Fluoro-5-Nitrobenzoate
CAS No.	850807-07-7
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	3-Fluoro-5-nitrobenzoic acid ethyl ester; Ethyl 3-fluoro-5-nitrobenzoate; Benzoic acid, 3-fluoro-5-nitro-, ethyl ester; 850807-07-7; Ethyl 3-fluoro-5-nitrobenzoate; 3-Fluoro-5-nitro-benzoic acid ethyl ester; Ethyl 3-Fluoro-5-Nitrobenzoate; 5-Nitro-3-fluorobenzoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoro-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.