Description

1-((4-Fluorophenyl)Carbamoyl)Cyclopropanecarboxylic Acid CAS NO 849217-48-7 is a high-purity, advanced pharmaceutical intermediate featuring a cyclopropane carboxylic acid core linked to a 4-fluorophenyl carbamoyl group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile building block for medicinal chemistry research and process development. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorophenyl moiety for enhanced bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker for the development of chemical probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced materials with unique thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and scale-up process development.

Basic Information

Product Name	1-((4-Fluorophenyl)Carbamoyl)Cyclopropanecarboxylic Acid
CAS No.	849217-48-7
Molecular Formula	C11H10FNO3
Molecular Weight	223.20 g/mol
Synonyms	Cyclopropanecarboxylic acid, 1-[(4-fluorophenyl)aminocarbonyl]-; 1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic acid; 1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid; 1-Carboxycyclopropanecarboxylic acid 4-fluoroanilide; N-(4-Fluorophenyl)-1-carboxycyclopropanecarboxamide; 849217-48-7; FC-CPCA
EINECS	Contact for details

Quality Control

Our 1-((4-Fluorophenyl)Carbamoyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.