Description

2-Methoxy-4-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid building block distinguished by its methoxy and trifluoromethoxy substituents. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique electronic and steric properties can modulate biological activity and material characteristics. It is primarily sought by research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer Modification: Incorporated into polymer chains to impart specific properties such as improved thermal stability, chemical resistance, or unique solubility profiles.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and amide bond formations to create complex molecular architectures for research and scale-up.
• Coordination Chemistry Ligand: The carboxylic acid functionality allows it to act as a ligand for metal complexes in catalytic and material science applications.

Basic Information

Product Name	2-Methoxy-4-(Trifluoromethoxy)Benzoic Acid
CAS No.	848947-91-1
Molecular Formula	C9H7F3O4
Molecular Weight	236.15 g/mol
Synonyms	4-(Trifluoromethoxy)-2-methoxybenzoic acid; 2-Methoxy-4-trifluoromethoxybenzoic acid; Benzoic acid, 2-methoxy-4-(trifluoromethoxy)-; 848947-91-1; 2-Methoxy-α,α,α-trifluoro-p-anisic acid; 4-(Trifluoromethoxy)-o-anisic acid; 2-Methoxy-4-(trifluoromethoxy)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Trifluoromethoxy)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and advanced material synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.