Description

2-(Benzyloxy)-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular structure, which combines a benzyl-protected phenolic ether with a carboxylic acid group and a fluorine atom, enabling precise modifications in complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for electron-transport or host materials in OLED device fabrication.
• Polymer Chemistry: Utilized as a monomer or modifier to introduce fluorine and aromatic functionality into specialty polymers, improving thermal and chemical resistance.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-(Benzyloxy)-5-Fluorobenzoic Acid
CAS No.	847256-14-8
Molecular Formula	C14H11FO3
Molecular Weight	246.24 g/mol
Synonyms	5-Fluoro-2-(phenylmethoxy)benzoic Acid; Benzoic acid, 5-fluoro-2-(phenylmethoxy)-; 2-Benzyloxy-5-fluorobenzoic Acid; 5-Fluoro-2-benzyloxybenzoic Acid; 2-(Benzyloxy)-5-fluorobenzoic acid; 847256-14-8; 2-(Phenylmethoxy)-5-fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.