Description

3-Fluoro-4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity, multifunctional biphenyl derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of fluorine and trifluoromethyl substituents, which are essential for modulating the electronic properties, metabolic stability, and lipophilicity of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly non-steroidal anti-inflammatory drugs (NSAIDs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially non-steroidal anti-inflammatory drugs (NSAIDs) and kinase inhibitors.
• Agrochemical Synthesis: Used in constructing advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorine-containing liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the synthesis of organic semiconductors and charge-transport materials for OLEDs and OFETs.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for introducing fluorinated aromatic units into high-performance polymers.
• Chemical Research & Development: A versatile scaffold in medicinal and materials chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Fluoro-4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	845826-91-7
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	[1,1'-Biphenyl]-4-carboxylic acid, 3-fluoro-4'-(trifluoromethyl)-; 3-Fluoro-4'-(trifluoromethyl)biphenyl-4-carboxylic acid; 4'-Trifluoromethyl-3-fluorobiphenyl-4-carboxylic acid; 3-Fluoro-4'-(trifluoromethyl)-1,1'-biphenyl-4-carboxylic acid; 845826-91-7; 3-Fluoro-4'-(trifluoromethyl)biphenyl-4-carboxylic acid; 4-Carboxy-3-fluoro-4'-trifluoromethylbiphenyl
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.