Description

cis-2-(3,5-Difluorobenzoyl)Cyclohexane-1-Carboxylic Acid is a high-purity, fluorinated carboxylic acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and functional groups make it an invaluable intermediate for constructing complex molecules with specific biological activity. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, where its unique structure enables the fine-tuning of potency and selectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the difluorobenzoyl moiety contributes to enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, leveraging its rigid cyclohexane backbone and fluorine atoms.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes to study enzyme mechanisms and protein interactions.

Basic Information

Item	Detail
Product Name	cis-2-(3,5-Difluorobenzoyl)Cyclohexane-1-Carboxylic Acid
CAS No.	844856-71-9
Molecular Formula	C14H14F2O3
Molecular Weight	268.26 g/mol
Synonyms	cis-2-(3,5-Difluorobenzoyl)cyclohexanecarboxylic acid; (1R,2S)-rel-2-(3,5-Difluorobenzoyl)cyclohexanecarboxylic acid; 2-(3,5-Difluorobenzoyl)cyclohexanecarboxylic acid (cis isomer); Cyclohexanecarboxylic acid, 2-(3,5-difluorobenzoyl)-, cis-; 844856-71-9; cis-2-(3,5-Difluorobenzoyl)-1-cyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our cis-2-(3,5-Difluorobenzoyl)Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (cis isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.