Description

4-Bromo-6-Fluorobenzo[B]Thiophene-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which serves as a critical precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small molecule drugs, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity of the benzothiophene core.
• Material Science Precursor: Serves as a building block for organic semiconductors, liquid crystals, and other functional organic materials due to its electron-rich thiophene ring.
• Chemical Research & Development: Employed in academic and industrial labs for method development, such as cross-coupling reactions (Suzuki, Buchwald-Hartwig) and derivatization studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-Bromo-6-Fluorobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	826995-60-2
Molecular Formula	C9H4BrFO2S
Molecular Weight	275.09 g/mol
Synonyms	4-Bromo-6-fluorobenzo[b]thiophene-2-carboxylic acid; 6-Fluoro-4-bromobenzo[b]thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-bromo-6-fluorobenzo[b]thiophene-; Benzo[b]thiophene-2-carboxylic acid, 4-bromo-6-fluoro-; 826995-60-2; 4-Bromo-6-fluoro-1-benzothiophene-2-carboxylic acid; 4-Bromo-6-fluorobenzothiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-6-Fluorobenzo[B]Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.