Description

Methyl 4-Fluoro-3-(Hydroxymethyl)Benzoate is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive hydroxymethyl group and a fluorine atom on the benzoate core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries. It serves as a key precursor for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Polymer Modification: Employed to introduce fluorinated benzoate groups into polymer chains, altering material properties like chemical resistance and surface energy.
• Organic Synthesis & Chemical Research: A valuable reagent for academic and industrial research in medicinal chemistry and material science.
• Fluorine-Containing Fine Chemical Production: Acts as a versatile intermediate for manufacturing various specialty fluorinated fine chemicals and dyes.

Basic Information

Product Name	Methyl 4-Fluoro-3-(Hydroxymethyl)Benzoate
CAS No.	816449-69-1
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	Benzoic acid, 4-fluoro-3-(hydroxymethyl)-, methyl ester; Methyl 4-fluoro-3-(hydroxymethyl)benzoate; 3-(Hydroxymethyl)-4-fluorobenzoic acid methyl ester; Methyl 3-(hydroxymethyl)-4-fluorobenzoate; 4-Fluoro-3-(hydroxymethyl)benzoic acid methyl ester; 816449-69-1; MFCD28409084
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Fluoro-3-(Hydroxymethyl)Benzoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our facilities operate under cGMP principles suitable for pharmaceutical intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.