Description

Resolvin D2 is a specialized pro-resolving lipid mediator (SPM) derived from the ω-3 fatty acid docosahexaenoic acid (DHA). This compound plays a critical role in the active resolution of inflammation, offering a targeted mechanism distinct from conventional immunosuppression. It is essential for research and development in the pharmaceutical and biotechnology sectors, particularly for programs focused on inflammatory and autoimmune diseases. The high-purity material, CAS NO 810668-37-2, is supplied to support advanced therapeutic discovery and analytical standard preparation.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate for developing novel anti-inflammatory therapeutics.
• Biochemical Research: For in vitro and in vivo studies investigating the molecular mechanisms of inflammation resolution and immune modulation.
• Analytical Standard: Used as a high-purity calibrant in LC-MS, HPLC, and other analytical methods for quantifying Resolvin pathways in biological samples.
• Preclinical Studies: Essential for efficacy and pharmacokinetic testing in animal models of chronic inflammatory conditions.
• Cell Culture & Signaling Studies: Applied to study specific receptor interactions (e.g., GPR18/DRV2) and downstream cellular responses.
• Nutraceutical & Cosmeceutical Innovation: Exploration of advanced formulations targeting resolution physiology for topical or dietary applications.

Basic Information

Product Name	Resolvin D2
CAS No.	810668-37-2
Molecular Formula	C22H32O5
Molecular Weight	376.49 g/mol
Synonyms	RvD2; 7S,16R,17S-Trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid; Resolvin D2; (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-Trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid; PD1; Protectin D1 (isomeric); Specialized Pro-resolving Mediator D2; Docosahexaenoic Acid-derived Mediator.
EINECS	Contact for details

Quality Control

Our Resolvin D2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and LC-MS for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support research requiring compliance with cGMP guidelines for API starting materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.