Description

1,4-Methano-1H-3-Benzazepin-5-Ol,1Bta-Ethyl-2,3,4Bta,5-Tetrahydro-5Bta-Methyl-(8Ci) is a complex, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound, identified by CAS number 802269-64-3, is valued for its unique benzazepine core structure, which serves as a critical scaffold for creating novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of new chemical entities targeting central nervous system and other disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Reference Standard: Employed as an analytical standard for method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Biochemical Tool Compound: Utilized in vitro and in vivo to study specific biological pathways and mechanisms of action.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	1,4-Methano-1H-3-Benzazepin-5-Ol,1Bta-Ethyl-2,3,4Bta,5-Tetrahydro-5Bta-Methyl-(8Ci)
CAS No.	802269-64-3
Molecular Formula	C15H21NO
Molecular Weight	231.33 g/mol
Synonyms	1β-Ethyl-2,3,4β,5-tetrahydro-5β-methyl-1,4-methano-1H-3-benzazepin-5-ol; 1,4-Methano-1H-3-benzazepin-5-ol, 1β-ethyl-2,3,4β,5-tetrahydro-5β-methyl-; 1β-Ethyl-5β-methyl-2,3,4β,5-tetrahydro-1,4-methano-1H-3-benzazepin-5-ol; 1β-Ethyl-5β-methyl-1,4-methano-1H-3-benzazepin-5-ol; 802269-64-3; Benzazepine derivative intermediate; 5β-Methyl-1β-ethyl-1,4-methano-1H-3-benzazepin-5-ol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (typically ≥97% by area normalization), to ensure consistency and reliability for critical research applications. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client requirements or regulatory standards for investigational use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.