Description

Methyl 5-(4-Fluorophenyl)Oxazole-4-Carboxylate is a high-value fluorinated oxazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated heterocyclic motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorophenyl-oxazole core can contribute to bioactivity and environmental stability.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Methyl 5-(4-Fluorophenyl)Oxazole-4-Carboxylate
CAS No.	89204-90-0
Molecular Formula	C11H8FNO3
Molecular Weight	221.19 g/mol
Synonyms	Methyl 5-(4-fluorophenyl)-1,3-oxazole-4-carboxylate; 5-(4-Fluorophenyl)oxazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-5-(4-fluorophenyl)oxazole; Methyl 5-(p-fluorophenyl)oxazole-4-carboxylate; 89204-90-0; 5-(4-Fluorophenyl)-4-oxazolecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(4-Fluorophenyl)Oxazole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.