Description

5-Fluoro-1-Benzofuran-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine can dramatically alter biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the benzofuran scaffold contributes to efficacy.
• Material Science Research: Serves as a building block for developing novel fluorinated organic electronic materials, liquid crystals, and polymers.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	5-Fluoro-1-Benzofuran-2-Carboxylic Acid
CAS No.	89197-62-6
Molecular Formula	C9H5FO3
Molecular Weight	180.13 g/mol
Synonyms	5-Fluorobenzofuran-2-carboxylic acid; 2-Benzofurancarboxylic acid, 5-fluoro-; 5-Fluoro-2-benzofurancarboxylic acid; 5-Fluorobenzo[b]furan-2-carboxylic acid; 5-Fluoro-1-benzofurane-2-carboxylic acid; 5-F-BFC Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Benzofuran-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.