Description

Dabsyl-Glycine is a high-purity chemical derivative of glycine, specifically designed for advanced analytical and synthetic applications. Its primary value lies in its role as a key reagent for the derivatization of amino acids, enabling highly sensitive detection and quantification in complex matrices. This product is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors who require precise and reliable analytical standards.

Application

• Amino Acid Analysis: As a pre-column derivatization agent for the HPLC and LC-MS analysis of amino acids, enhancing detection sensitivity and chromatographic separation.
• Biomarker Research: Used in metabolomic studies to tag and identify low-abundance metabolites in biological fluids like plasma and urine.
• Peptide Synthesis & Modification: Serves as a protected glycine derivative or a building block in the synthesis of specialized peptides and peptide conjugates.
• Pharmaceutical QC: Employed in the quality control of protein-based therapeutics and amino acid formulations to ensure purity and consistency.
• Food & Feed Analysis: Applied in the accurate determination of amino acid profiles in nutritional supplements, infant formula, and animal feed.
• Diagnostic Reagent Manufacturing: A critical component in the formulation of diagnostic kits for inborn errors of metabolism and other clinical assays.

Basic Information

Product Name	Dabsyl-Glycine
CAS No.	89131-05-5
Molecular Formula	C14H14N4O4S
Molecular Weight	334.35 g/mol
Synonyms	4-Dimethylaminoazobenzene-4'-sulfonylglycine; DABS-Gly; Dabsyl glycine; Glycine, N-[4-[(4-dimethylamino)phenyl]azo]benzenesulfonyl]-; N-Dabsylglycine; DABS-Gly-OH; Dabsyl-Gly; 4'-Dimethylaminoazobenzene-4-sulfonylglycine
EINECS	Contact for details

Quality Control

Our Dabsyl-Glycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.