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6-(2-(3-(5-Chloro-3,4-Dihydroxybenzoyl)-3-(3-Hydroxypropyl)-1-Ureido)-2-Phenylacetamido)Penicillanic Acid CAS NO 88852-54-4


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CAS No.:88852-54-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(2-(3-(5-Chloro-3,4-Dihydroxybenzoyl)-3-(3-Hydroxypropyl)-1-Ureido)-2-Phenylacetamido)Penicillanic Acid is a sophisticated β-lactam derivative, representing a key advanced intermediate in modern pharmaceutical synthesis. Its complex structure is engineered to serve as a crucial building block for the development of novel, high-potency antibiotics and other therapeutic agents. This compound is primarily targeted at research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation antibacterial drugs and specialized active pharmaceutical ingredients (APIs).

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel penicillin and cephalosporin-based antibiotics with enhanced efficacy.
  • Antibacterial Drug Research: Used in medicinal chemistry for the design and development of new β-lactamase inhibitors and combination therapies.
  • API Synthesis: Serves as a key building block in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs).
  • Biochemical Research: Employed in studies investigating bacterial resistance mechanisms and the structure-activity relationships (SAR) of β-lactam compounds.
  • Fine Chemical Production: Utilized in contract manufacturing organizations (CMOs) for the custom synthesis of specialized chemical entities.

Basic Information

Item Details
Product Name 6-(2-(3-(5-Chloro-3,4-Dihydroxybenzoyl)-3-(3-Hydroxypropyl)-1-Ureido)-2-Phenylacetamido)Penicillanic Acid
CAS No. 88852-54-4
Molecular Formula C30H29ClN4O8S
Molecular Weight 657.09 g/mol
Synonyms 6-[[[2-[[[3-(5-Chloro-3,4-dihydroxybenzoyl)-3-(3-hydroxypropyl)ureido]phenylacetyl]amino]]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-[(2R)-2-[[3-(5-Chloro-3,4-dihydroxybenzoyl)-3-(3-hydroxypropyl)ureido](phenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Penicillanic acid derivative intermediate; Advanced β-lactam intermediate
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Quality Control

Our 6-(2-(3-(5-Chloro-3,4-Dihydroxybenzoyl)-3-(3-Hydroxypropyl)-1-Ureido)-2-Phenylacetamido)Penicillanic Acid is produced under strict quality management systems suitable for pharmaceutical intermediate applications. All batches undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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