Description

Argipressin, β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid(1)-Ile(2)-Abu(4)- is a synthetic analog of the neurohypophysial hormone vasopressin, engineered for enhanced stability and specific receptor binding affinity. This compound is critical for advanced pharmaceutical research and development, particularly in the study of cardiovascular and renal systems. It is primarily utilized by research institutions, pharmaceutical developers, and contract manufacturing organizations (CMOs) focused on peptide-based therapeutics and diagnostic agents.

Application

• Pharmaceutical Research: As a key reference standard and active pharmaceutical ingredient (API) in preclinical studies for vasopressin receptor (V1a, V2) modulation.
• Therapeutic Development: Investigational use in the development of novel treatments for conditions like diabetes insipidus, septic shock, and bleeding disorders.
• Biochemical Research: A vital tool for studying G-protein-coupled receptor (GPCR) signaling pathways, cellular water transport, and vascular physiology.
• Diagnostic Agent Synthesis: Used in the creation of labeled compounds for imaging and diagnostic assays.
• Peptide Chemistry Studies: Serves as a model compound for studying structure-activity relationships (SAR) in modified peptide hormones.

Basic Information

Product Name	Argipressin, β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid(1)-Ile(2)-Abu(4)-
CAS No.	88686-52-6
Molecular Formula	C46H65N13O12S2
Molecular Weight	1040.2 g/mol
Synonyms	1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid)-2-isoleucine-4-aminobutyric acid-8-arginine-vasopressin; [1-β-Mercapto-β,β-cyclopentamethylenepropionic acid, 2-isoleucine, 4-aminobutyric acid]vasopressin; Desmopressin Impurity F; d(CH2)5[D-Ile2, Abu4]AVP; Vasopressin V1a receptor antagonist; β-Mercapto-β,β-cyclopentamethylenepropionyl1-Ile2-Abu4-Arg8-vasopressin; Cyclopentamethylene-β-mercaptopropionic acid1-Ile2-Abu4-AVP.
EINECS	Contact for details

Quality Control

Our Argipressin, β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid(1)-Ile(2)-Abu(4)- is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and amino acid analysis to ensure it meets rigorous standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.