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Argipressin, (1-Mercaptocyclohexaneacetic Acid)(1)-Ile(2)-Val(4)- CAS NO 81094-06-6


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CAS No.:81094-06-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Argipressin, (1-Mercaptocyclohexaneacetic Acid)(1)-Ile(2)-Val(4)- is a synthetic analogue of the endogenous neurohypophysial hormone vasopressin, specifically engineered for enhanced stability and targeted pharmacological activity. This high-purity peptide is critical for research and development in advanced therapeutic areas, offering a reliable tool for studying vasopressin receptor interactions and developing novel treatments. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on endocrinology, cardiovascular research, and metabolic disorders.

Application

  • Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) in preclinical studies for vasopressin-related therapies.
  • Biochemical Assay Development: Used in the development and validation of high-throughput screening (HTS) assays for vasopressin receptor (V1a, V1b, V2) activity.
  • Endocrinology Studies: Investigation of the role of vasopressin in water balance, blood pressure regulation, and stress response mechanisms.
  • Metabolic Disorder Research: Exploration of potential therapeutic applications for conditions like diabetes insipidus and syndrome of inappropriate antidiuretic hormone secretion (SIADH).
  • Cardiovascular Research: Study of vasoconstrictive effects and potential applications in managing hypotension or as a vasopressor agent.
  • Neuroscience: Research into the central nervous system effects of vasopressin, including social behavior, memory, and autonomic functions.

Basic Information

Product Name Argipressin, (1-Mercaptocyclohexaneacetic Acid)(1)-Ile(2)-Val(4)-
CAS No. 81094-06-6
Molecular Formula C46H65N13O12S2
Molecular Weight 1048.2 g/mol
Synonyms [1-Deamino-4-valine, 8-D-arginine] Vasopressin; Desmopressin analogue; dDAVP analogue; 1-(Mercaptocyclohexaneacetic acid)-2-isoleucine-4-valine-8-D-arginine vasopressin; Cyclo(1-6)-Cys(1)-Ile(2)-Val(4)-Arg(8)-vasopressin; (1-β-Mercapto-β,β-cyclopentamethylenepropionic acid)-2-isoleucine-4-valine-8-D-arginine vasopressin; AVP analogue; Vasopressin V2 receptor agonist analogue.
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Quality Control

Our Argipressin analogue is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Quality assurance protocols align with cGMP principles where applicable, and specifications can be tailored to meet specific project requirements. COAs are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive). Store in a cool, dry place. Keep container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 98.0%
Single Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 2.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%
Acetic Acid Content (HPLC) ≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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