Description

Desmopressin Acetate is a synthetic analogue of the natural hormone vasopressin, specifically engineered for enhanced antidiuretic potency with reduced pressor activity. This high-purity peptide is critical for ensuring consistent therapeutic efficacy and safety in pharmaceutical formulations. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors for producing treatments for central diabetes insipidus, nocturnal enuresis, and certain bleeding disorders.

Application

• Pharmaceutical Active Ingredient (API): Core component in injectable and intranasal formulations for the treatment of central diabetes insipidus.
• Hemophilia & Bleeding Disorder Therapy: Used to manage mild to moderate hemophilia A and von Willebrand's disease by increasing plasma levels of factor VIII.
• Nocturnal Enuresis Treatment: Incorporated into medications designed to reduce bedwetting in children.
• Diagnostic Agent: Employed in renal function tests and for the differential diagnosis of diabetes insipidus.
• Biochemical Research: Serves as a critical reference standard and tool in endocrinology and pharmacology research.
• Veterinary Medicine: Used in the management of diabetes insipidus in companion animals.

Basic Information

Product Name	Desmopressin Acetate
CAS No.	62357-86-2
Molecular Formula	C46H64N14O12S2 • xC2H4O2
Molecular Weight	1129.26 (anhydrous free base)
Synonyms	1-Desamino-8-D-arginine vasopressin acetate; DDAVP; Adiuretin; Minirin; Desmogalen; Deamino-8-D-Arginine Vasopressin; Argipressin, 1-deamino-8-D-arginine-, acetate; Vasopressin, 1-desamino-8-D-arginine-, acetate
EINECS	263-552-2

Quality Control

Our Desmopressin Acetate is manufactured under strict quality management systems. Each batch is tested to meet stringent specifications, including identity, purity, and potency, aligning with pharmacopeial standards (e.g., USP, EP). A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance for our pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in its original packaging under dry conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous, acetic acid-free basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 6.0%
Acetic Acid Content	5.0% - 12.0%
Bacterial Endotoxins	< 50 IU/mg
Microbial Enumeration	Conforms to EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.