Description

Vasopressin, 8-L-Lysine-, Monoacetate (Salt) is a synthetic analogue of the endogenous antidiuretic hormone, arginine vasopressin, where the arginine at position 8 is substituted with lysine. This modification provides a compound with distinct pharmacological properties, making it a critical intermediate and active pharmaceutical ingredient (API) for research and therapeutic development. It is essential for pharmaceutical manufacturers and research institutions focused on endocrinology, renal function, and cardiovascular research. The product is supplied as a high-purity monoacetate salt to ensure stability and consistent performance.

Application

• Pharmaceutical API: Used as the active ingredient in the formulation of specific therapeutic agents.
• Biomedical Research: A key tool for studying vasopressin receptor (V1a, V1b, V2) signaling pathways and physiological responses.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical labs.
• Peptide Chemistry Studies: Utilized in research exploring structure-activity relationships (SAR) of vasopressin analogues.
• Diagnostic Development: Potential use in the development of diagnostic assays for disorders related to water balance and blood pressure regulation.

Basic Information

Product Name	Vasopressin, 8-L-Lysine-, Monoacetate (Salt)
CAS No.	83968-49-4
Molecular Formula	C48H68N14O13S2 • C2H4O2
Molecular Weight	1129.3 g/mol (for monoacetate salt)
Synonyms	8-Lysine Vasopressin Monoacetate; Lypressin Acetate; Lysine Vasopressin Acetate; [Lys8]-Vasopressin Acetate; 8-Lys-Vasopressin Acetate; Postacton (historical brand); Diapid (historical brand); Nα-Glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide cyclic (1→6)-disulfide monoacetate
EINECS	Contact for details

Quality Control

Our Vasopressin, 8-L-Lysine-, Monoacetate (Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, peptide content determination, and identity confirmation via mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	5.0% - 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.