Description

Desmopressin is a synthetic analogue of the natural pituitary hormone vasopressin, recognized for its potent and selective antidiuretic activity. This high-purity peptide is critical for pharmaceutical manufacturing, offering enhanced stability and a longer duration of action compared to its natural counterpart. It is an essential active pharmaceutical ingredient (API) for global producers of medications targeting central diabetes insipidus, nocturnal enuresis, and certain bleeding disorders like hemophilia A and von Willebrand's disease.

Application

• Pharmaceutical API: Primary active ingredient in prescription medications for the treatment of central diabetes insipidus.
• Nocturnal Enuresis Treatment: Used in formulations to manage bed-wetting by reducing urine production during sleep.
• Hemostasis Management: Employed in drugs to increase factor VIII and von Willebrand factor levels for patients with mild hemophilia A or von Willebrand's disease.
• Diagnostic Aid: Utilized in renal function tests and for the differential diagnosis of polyuria-polydipsia syndromes.
• Research & Development: Serves as a key reference standard and biochemical tool in endocrine and renal research.
• Formulation Development: Used in the development of novel drug delivery systems, including nasal sprays, injectables, and oral tablets.

Basic Information

Product Name	Desmopressin
CAS No.	62288-83-9
Molecular Formula	C46H64N14O12S2
Molecular Weight	1069.2 g/mol
Synonyms	1-Desamino-8-D-arginine vasopressin; DDAVP; Adiuretin; Desmogalen; Minirin; Octostim; Deamino-8-D-arginine vasopressin; Desmopressin acetate (common salt form)
EINECS	263-489-6

Quality Control

Our Desmopressin is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards (e.g., USP, EP). Comprehensive analytical testing, including HPLC for assay and related substances, is performed. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in the original desiccated packaging to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 6.0%
Residue on Ignition	≤ 1.0%
Bacterial Endotoxins	< 50 IU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.