Description

Desmopressin Acetate is a synthetic analogue of the natural hormone vasopressin, specifically engineered for enhanced antidiuretic potency with minimal pressor activity. This high-purity peptide is critical for ensuring consistent therapeutic efficacy and safety in pharmaceutical formulations. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors for the production of treatments for central diabetes insipidus, nocturnal enuresis, and certain bleeding disorders.

Application

• Pharmaceutical Active Ingredient (API): Core component in injectable and intranasal formulations for the treatment of central diabetes insipidus.
• Hemophilia & von Willebrand Disease Management: Used to increase plasma levels of factor VIII and von Willebrand factor to control bleeding episodes.
• Nocturnal Enuresis Treatment: Incorporated into medications to reduce nighttime bedwetting.
• Diagnostic Agent: Employed in renal function tests and for the differential diagnosis of diabetes insipidus.
• Research & Development: Serves as a reference standard and key reagent in biochemical and pharmacological research on vasopressin receptors.
• Veterinary Medicine: Used in the treatment of diabetes insipidus in companion animals.

Basic Information

Product Name	Desmopressin Acetate
CAS No.	16789-98-3
Molecular Formula	C46H64N14O12S2 • xC2H4O2
Molecular Weight	1129.26 (base), 1329.59 (as triacetate)
Synonyms	1-Desamino-8-D-arginine vasopressin acetate; DDAVP Acetate; Adiuretin; Minirin; Desmopressin; Deamino-8-D-arginine vasopressin; Argipressin, 1-deamino-8-D-arginine-, acetate; Vasopressin, 1-desamino-8-D-arginine-, acetate
EINECS	240-849-1

Quality Control

Our Desmopressin Acetate is manufactured under strict quality systems. Each batch is tested to ensure compliance with relevant pharmacopoeial standards such as USP, EP, and BP. Comprehensive testing includes identity, purity, assay, and specific tests for related substances and residual solvents. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous, acetic acid-free basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 6.0%
Acetic Acid Content	5.0% - 12.0%
Bacterial Endotoxins	< 50 IU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.