Description

Mozavaptan Hydrochloride is a selective, non-peptide vasopressin V2 receptor antagonist. This compound is of significant interest in pharmaceutical research and development, particularly for its potential therapeutic applications in managing conditions related to fluid and electrolyte imbalance. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel diuretics and treatments for hyponatremia. The high-purity material is essential for preclinical studies, formulation development, and analytical method validation.

Application

• Pharmaceutical Research & Development: Serves as a key active pharmaceutical ingredient (API) intermediate or reference standard in the development of vasopressin receptor antagonist drugs.
• Preclinical Studies: Used in in vitro and in vivo studies to investigate the pharmacology, efficacy, and safety profile of V2 receptor blockade.
• Analytical Method Development: Employed as a high-purity standard for developing and validating HPLC, LC-MS, and other chromatographic assays for quality control.
• Formulation Development: Utilized in creating dosage form prototypes, such as tablets or capsules, for pharmacokinetic and stability testing.
• Biochemical Research: Acts as a specific tool compound in receptor binding assays and signal transduction studies to understand vasopressin pathways.
• Chemical Synthesis: Functions as a critical building block or precursor for the synthesis of novel analogs and derivatives for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Mozavaptan Hydrochloride
CAS No.	138470-70-9
Molecular Formula	C₂₆H₂₆ClN₃O₃ • HCl
Molecular Weight	500.87 g/mol
Synonyms	OPC-31260; Mozavaptan HCl; 5-Dimethylamino-1-[4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine Hydrochloride; YM-087 Hydrochloride; Benzazepine, 5-(dimethylamino)-2,3,4,5-tetrahydro-1-[4-[[(2-methylbenzoyl)amino]benzoyl]]-, hydrochloride (1:1); Vaprisol (Brand Name for the drug substance); OPC31260
EINECS	Contact for details

Quality Control

Our Mozavaptan Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results for key parameters such as assay, related substances, residual solvents, and identification. We support compliance with cGMP standards for API intermediates where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.