Description

Argipressin, Phe(2)- CAS NO 30635-27-9 is a synthetic analogue of the neurohypophysial hormone arginine vasopressin, specifically modified at the second phenylalanine position. This modification is critical for research into receptor selectivity and the development of novel therapeutic agents targeting vasopressin pathways. It is an essential high-purity reference standard and intermediate for pharmaceutical R&D, particularly for researchers and manufacturers focused on endocrinology, cardiovascular, and renal function.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and building block for investigating vasopressin receptor (V1a, V1b, V2) pharmacology and signal transduction.
• Peptide Synthesis: Used as a critical intermediate in the solid-phase or solution-phase synthesis of more complex vasopressin analogues and conjugates.
• Biochemical Assays: Employed in competitive binding assays, enzyme-linked immunosorbent assays (ELISAs), and other in vitro studies to characterize antibody specificity or receptor affinity.
• Metabolic Studies: Utilized in research models to study the role of vasopressin in water homeostasis, blood pressure regulation, and stress response.
• Quality Control: Acts as a system suitability standard and impurity marker in the analytical testing of commercial vasopressin-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Argipressin, Phe(2)- CAS NO 30635-27-9
CAS No.	30635-27-9
Molecular Formula	C₄₆H₆₅N₁₅O₁₂S₂
Molecular Weight	1084.2 g/mol
Synonyms	[Phe²]-Argipressin; [Phenylalanine²]-Vasopressin; 1-(3-Mercaptopropanoic acid)-2-(L-phenylalanine)-8-L-arginine vasopressin; Desmopressin analogue; AVP analogue; Argipressin (Phe²) acetate; Vasopressin, 2-phenylalanine-
EINECS	Contact for details

Quality Control

Our Argipressin, Phe(2)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Acetate Content (HPLC/IC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.