Description

Actaplanin-A is a complex glycopeptide antibiotic belonging to the actaplanin family, identified by CAS NO 88357-81-7. This compound is valued for its potent antibacterial activity, particularly against Gram-positive bacteria, making it a critical intermediate and reference standard in antibiotic research and development. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel antibiotic therapies.
• Microbiological Studies: Used as a potent tool compound to study bacterial cell wall synthesis, mechanisms of antibiotic action, and the emergence of resistance in Gram-positive pathogens.
• Biochemical Reagent Manufacturing: Supplied as a high-purity biochemical for use in enzymatic assays and other life science research applications.
• Quality Control & Analytical Testing: Employed as a certified reference material (CRM) in HPLC, LC-MS, and other analytical methods for quality assurance in antibiotic production.

Basic Information

Product Name	Actaplanin-A
CAS No.	88357-81-7
Molecular Formula	C72H88Cl2N8O32
Molecular Weight	1626.3 g/mol (approx.)
Synonyms	Actaplanin A; Antibiotic A-4696; A-4696; L 17046; Antibiotic L 17046; Actaplanin; (2S)-2-[[(6S,9S,12S,15R,18S,21S,24S,30S,33S,36S,39S,42S,45S,51S,54S,57S,60S,63S,66S,69S,72S)-72-[[(2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S,44S,47S,50S,53S,56S,59S,62S,65S,68S,71S)-71-Acetamido-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68-henicosahydroxy-2,68-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70-tetracosaoxo-1,3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tetratetracontaazacyclotetratetracontan-71-yl]methyl]-30,33,36,39,42,45,51,54,57,60,63,66,69-tridecahydroxy-6,9,12,15,18,21,24-heptamethyl-3,27,48,72-tetraoxo-1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70-tetracosaazacyclooctatetracontan-2-yl]formamido]-3-(4-hydroxyphenyl)propanoic acid
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Quality Control

Our Actaplanin-A is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.