Description

Poly(2-Methylthio-7-Deazainosinic Acid) is a synthetic, modified nucleoside derivative with significant potential in advanced biochemical research and pharmaceutical development. This compound matters as a key building block for the synthesis of oligonucleotide analogs, enabling the study of nucleic acid structure, function, and therapeutic targeting. It is primarily needed by research institutions and pharmaceutical companies engaged in developing novel antiviral agents, antisense oligonucleotides, and other nucleic acid-based therapeutics.

Application

• Oligonucleotide Synthesis: Serves as a critical monomer for constructing modified DNA/RNA strands with enhanced stability or specific binding properties.
• Antiviral Research: Investigated as a potential precursor or analog in the development of nucleoside-based antiviral drugs targeting viral polymerases.
• Biochemical Probes: Used to create labeled or functionalized probes for studying enzyme mechanisms, such as those of methyltransferases and polymerases.
• Antisense Technology: Incorporated into antisense oligonucleotides to modulate gene expression for therapeutic and research applications.
• Medicinal Chemistry: Acts as a scaffold for structure-activity relationship (SAR) studies in drug discovery programs focused on nucleoside targets.
• Diagnostic Development: Potential use in the design of molecular diagnostic tools and sensors that rely on specific nucleic acid interactions.

Basic Information

Product Name	Poly(2-Methylthio-7-Deazainosinic Acid)
CAS No.	88357-67-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Methylthio-7-deazainosinic Acid Polymer; 7-Deaza-2-(methylthio)inosinic Acid Polymer; Poly[2-(methylthio)-7-deazainosinic acid]; 2-(Methylthio)-7-deazainosine-5'-monophosphoric Acid Polymer; 7-Deaza-2-methylthioinosinic Acid Polymer; Poly(2-MeS-7-cHxI); Modified Nucleoside Polymer
EINECS	Contact for details

Quality Control

Our Poly(2-Methylthio-7-Deazainosinic Acid) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and MS are provided to guarantee reliable and reproducible performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Moisture Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, alkaline aqueous solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.