Description

(4,4'-Diaminopropionic Acid)Gramicidin S is a synthetic derivative of the natural antibiotic peptide Gramicidin S, modified with a diaminopropionic acid moiety. This structural modification is significant as it can enhance the compound's stability, solubility, and potentially alter its biological activity profile, making it a valuable tool for advanced research. It is primarily utilized by researchers in the pharmaceutical and biotechnology sectors for studying antimicrobial mechanisms, developing novel peptide-based therapeutics, and exploring structure-activity relationships.

Application

• Antimicrobial Research: Used as a reference standard or modified lead compound in studies targeting bacterial membranes and developing new antibiotics.
• Peptide Chemistry Studies: Serves as a model compound for investigating the effects of amino acid substitutions on peptide conformation, stability, and function.
• Biochemical Assay Development: Employed in the development and validation of assays for membrane disruption, ion channel activity, or cytotoxicity.
• Pharmaceutical R&D: Investigated for its potential in creating novel therapeutic agents with modified selectivity or reduced toxicity profiles.
• Academic Research: Utilized in university and institutional labs for fundamental research in microbiology, biophysics, and medicinal chemistry.

Basic Information

Product Name	(4,4'-Diaminopropionic Acid)Gramicidin S
CAS No.	87647-91-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Gramicidin S Derivative; Gramicidin S Analog; DAP-Gramicidin S; Cyclo(-Val-Orn-Leu-D-Phe-Pro-)2 derivative; (4,4'-DAP)Gramicidin S; Modified Gramicidin S; Antibiotic peptide derivative; Research peptide 87647-91-4
EINECS	Contact for details

Quality Control

Our (4,4'-Diaminopropionic Acid)Gramicidin S is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and consistency for your research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.