Description

2-Biphenyl-4'-Fluoro-Acetic Acid is a high-purity fluorinated biphenyl acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the biphenyl scaffold and fluorine substitution, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the biphenyl-fluorine motif enhances efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure for synthesizing fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and thermal stability.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to impart specific characteristics like enhanced weatherability, chemical resistance, or optical clarity to advanced polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and creating novel fluorinated compounds.
• Ligand & Catalyst Development: Utilized in the design of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.

Basic Information

Product Name	2-Biphenyl-4'-Fluoro-Acetic Acid
CAS No.	87293-37-6
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	2-(4'-Fluorobiphenyl-4-yl)acetic Acid; 4'-Fluoro-[1,1'-biphenyl]-4-acetic Acid; 2-(4'-Fluoro[1,1'-biphenyl]-4-yl)acetic Acid; 4-Fluorobiphenyl-4'-acetic Acid; 2-(4'-Fluoro-4-biphenylyl)acetic Acid; p-Fluorobiphenyl-4-acetic Acid; Biphenyl-4-acetic Acid, 4'-fluoro- derivative; FBPAA
EINECS	Contact for details

Quality Control

Our 2-Biphenyl-4'-Fluoro-Acetic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support development and scale-up with custom purity grades, from technical to research (>98%) and high-purity (>99%) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, handle with appropriate engineering controls and personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.