Description

1-Pyrrolidinepropanoic Acid, 8-Methyl-8-Azabicyclo(3.2.1)Oct-3-Yl Este R, Dihydrochloride, Endo- is a high-purity, complex organic salt with significant relevance in advanced pharmaceutical research and development. This compound is valued for its specific stereochemistry and functional groups, making it a critical intermediate or reference standard in the synthesis of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly those targeting neurological and receptor-specific pathways. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for your critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug molecules, especially in neurological and psychiatric drug discovery.
• Reference Standard: Used as an analytical standard in method development and validation for quality control (QC) and quality assurance (QA) laboratories.
• Biochemical Research: Employed in pharmacological studies as a ligand or probe to investigate receptor binding and enzyme inhibition mechanisms.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing reaction conditions during pre-clinical and clinical API manufacturing.
• Academic Research: A valuable compound for universities and research institutes conducting studies in medicinal chemistry and organic synthesis.
• Custom Synthesis Starting Material: Provides a sophisticated chiral scaffold for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	1-Pyrrolidinepropanoic Acid, 8-Methyl-8-Azabicyclo(3.2.1)Oct-3-Yl Este R, Dihydrochloride, Endo-
CAS No.	87168-45-4
Molecular Formula	C15H26N2O2 · 2HCl
Molecular Weight	347.30 g/mol (for dihydrochloride salt)
Synonyms	Endo-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1-pyrrolidinepropanoate dihydrochloride; Tropanyl 1-pyrrolidinepropionate dihydrochloride, endo-; 3-Tropanyl 3-pyrrolidinopropionate dihydrochloride; PPA Tropane Ester Dihydrochloride; 87168-45-4; (endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-(pyrrolidin-1-yl)propanoate dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 1-Pyrrolidinepropanoic Acid, 8-Methyl-8-Azabicyclo(3.2.1)Oct-3-Yl Este R, Dihydrochloride, Endo- is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical use. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. Certificates of Analysis (COA) detailing all specifications and results are available upon request and accompany each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.