Description

Imiloxan Hydrochloride is a selective α-2 adrenergic receptor antagonist of significant research and pharmaceutical interest. This compound is a crucial intermediate and reference standard in the development and quality control of neuropharmacological agents. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of active pharmaceutical ingredients (APIs) for applications in cardiovascular and central nervous system research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex neuroactive drug candidates.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control (QC/QA) of related pharmaceutical products.
• Biochemical Research: Employed as a selective tool compound in pharmacological studies to investigate α-2 adrenergic receptor function and signaling pathways.
• Preclinical Development: Utilized in animal model studies to explore potential therapeutic effects on blood pressure, mood, and cognitive function.
• Academic Research: Serves as a critical reagent in university and institutional labs for neuroscience and cardiovascular research projects.

Basic Information

Product Name	Imiloxan Hydrochloride
CAS No.	86710-23-8
Molecular Formula	C14H18N2O2 • HCl
Molecular Weight	282.77 g/mol
Synonyms	Imiloxan HCl; 2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride; RS-21361; (2S)-2-[(1,4-Benzodioxan-2-yl)methyl]-4,5-dihydro-1H-imidazole hydrochloride; (S)-Imiloxan hydrochloride; 2-[(2S)-1,4-Benzodioxan-2-ylmethyl]-4,5-dihydro-1H-imidazole hydrochloride; 2-(1,4-Benzodioxan-2-ylmethyl)-2-imidazoline monohydrochloride
EINECS	Contact for details

Quality Control

Our Imiloxan Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets the stringent requirements for research and pharmaceutical development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.