Description

Lenampicillin is a broad-spectrum, semi-synthetic aminopenicillin antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria. Its primary value lies in its enhanced oral bioavailability and stability compared to earlier penicillins, making it a critical active pharmaceutical ingredient (API) for therapeutic formulations. This compound is essential for manufacturers in the global pharmaceutical industry developing oral antibiotic medications to treat respiratory, urinary tract, and other bacterial infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of oral antibiotic tablets and capsules.
• Respiratory Infection Treatment: Formulated into medications targeting bronchitis, pneumonia, and other lower respiratory tract infections.
• Urinary Tract Infection (UTI) Treatment: Used in antibiotics designed to combat uncomplicated UTIs.
• Skin and Soft Tissue Infection Therapy: Incorporated into treatments for bacterial cellulitis and impetigo.
• Otolaryngology Medications: Applied in drugs for otitis media (middle ear infection) and sinusitis.
• Veterinary Antibiotics: Utilized in the development of antibacterial treatments for companion and livestock animals.
• Clinical Research: Serves as a reference standard and raw material in pharmacological studies and new drug development.

Basic Information

Product Name	Lenampicillin
CAS No.	86273-18-9
Molecular Formula	C21H23N5O6S
Molecular Weight	473.50 g/mol
Synonyms	Lenampicillin; KBT-1585; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2,2-dimethylpropanoyloxymethyl) ester; Varacillin; Talampicillin ester analogue; L-AMP-PC
EINECS	Contact for details

Quality Control

Our Lenampicillin is manufactured under strict quality management systems to ensure it meets the high-purity standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current Good Manufacturing Practices (cGMP) and can supply material that aligns with pharmacopeial standards for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.