Description

n-(3,5-Dinitrobenzoyl)Tyrosine is a specialized chiral derivatizing agent and a key synthetic intermediate. This compound matters for its critical role in the resolution and analytical determination of enantiomeric purity, particularly for amino acids and other chiral amines. It is primarily needed by pharmaceutical R&D laboratories, analytical chemistry service providers, and manufacturers of high-purity fine chemicals for applications in asymmetric synthesis and quality control.

Application

• Chiral Derivatizing Agent (CDA): Used for the preparation of diastereomeric derivatives to separate and analyze enantiomers via HPLC or other chromatographic methods.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex, optically active drug candidates and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Employed as a high-purity standard for method development and validation in chiral analysis.
• Biochemical Research: Utilized in studies involving tyrosine kinase inhibitors or as a modified amino acid probe in peptide research.
• Asymmetric Synthesis: Acts as a precursor or auxiliary in the synthesis of enantiomerically enriched compounds.
• Quality Control & Assurance: Critical for ensuring the enantiomeric purity of chiral substances in pharmaceutical and fine chemical manufacturing.

Basic Information

Product Name	n-(3,5-Dinitrobenzoyl)Tyrosine
CAS No.	86091-65-8
Molecular Formula	C16H13N3O8
Molecular Weight	375.29 g/mol
Synonyms	N-(3,5-Dinitrobenzoyl)-L-tyrosine; (S)-2-(3,5-Dinitrobenzamido)-3-(4-hydroxyphenyl)propanoic acid; L-Tyrosine, N-(3,5-dinitrobenzoyl)-; DNB-Tyrosine; 3,5-DNB-Tyr; 86091-65-8; Tyrosine, N-(3,5-dinitrobenzoyl)-
EINECS	Contact for details

Quality Control

Our n-(3,5-Dinitrobenzoyl)Tyrosine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive analytical and synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can support compliance needs for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.