Description

(5Alpha,8Alpha,9Alpha,11R*)-2,3-Dichloro-11-(Dimethylamino)-5,6,7,8,9,10-Hexahydro-5,9-Methanobenzocycloocten-8-Ol Hydrochloride is a complex, high-purity synthetic organic compound with a unique bridged polycyclic structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or active pharmaceutical ingredient (API) in specialized therapeutic areas. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of novel drug candidates. The compound, identified by CAS NO 85798-66-9, requires expert handling and precise quality control to ensure its integrity for sensitive applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex drug molecules, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a reference standard or a starting material in structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Preclinical Drug Development: Employed in the formulation and testing of new chemical entities (NCEs) during early-stage pharmacological evaluation.
• Fine Chemical Synthesis: Acts as a specialized reagent for constructing intricate molecular architectures in custom synthesis and process development.
• Biochemical Research: Potential use as a tool compound for investigating specific biological pathways and receptor interactions in vitro.

Basic Information

Item	Details
Product Name	(5Alpha,8Alpha,9Alpha,11R*)-2,3-Dichloro-11-(Dimethylamino)-5,6,7,8,9,10-Hexahydro-5,9-Methanobenzocycloocten-8-Ol Hydrochloride
CAS No.	85798-66-9
Molecular Formula	C₁₇H₂₂Cl₂N₂O • HCl
Molecular Weight	~377.74 g/mol (as hydrochloride salt)
Synonyms	2,3-Dichloro-11-(dimethylamino)-5,6,7,8,9,10-hexahydro-5,9-methanobenzocycloocten-8-ol hydrochloride; NSC 339579; 5,9-Methanobenzocycloocten-8-ol, 2,3-dichloro-11-(dimethylamino)-5,6,7,8,9,10-hexahydro-, hydrochloride, (5α,8α,9α,11R*)-; (5α,8α,9α,11R*)-2,3-Dichloro-11-(dimethylamino)-5,6,7,8,9,10-hexahydro-5,9-methanobenzocycloocten-8-ol HCl
EINECS	Contact for details

Quality Control

Our (5Alpha,8Alpha,9Alpha,11R*)-2,3-Dichloro-11-(Dimethylamino)-5,6,7,8,9,10-Hexahydro-5,9-Methanobenzocycloocten-8-Ol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters including assay (HPLC), impurity profile, and chiral purity where applicable. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.