Description

R(-)-n-Propylnorapomorphine Hydrobromide is a high-purity, enantiomerically pure chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and reference standard for the study of dopaminergic systems. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuroscience, neuropharmacology, and the development of central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug substance and product testing.
• Neuroscience Research: A key pharmacological tool for in vitro and in vivo studies targeting dopamine receptors, aiding in the understanding of receptor mechanisms and signaling pathways.
• Drug Discovery & Development: Serves as a chiral intermediate or lead compound in the synthesis and optimization of novel therapeutic agents for Parkinson's disease, schizophrenia, and other CNS disorders.
• Biochemical Assays: Employed in high-throughput screening (HTS) and binding assays to evaluate the potency and selectivity of new chemical entities.
• Academic Research: Utilized in university and institutional labs for fundamental pharmacological and neurochemical research projects.
• Metabolite Studies: Acts as a precursor or standard for investigating the metabolic fate and pharmacokinetic profiles of apomorphine-derived compounds.

Basic Information

Product Name	R(-)-n-Propylnorapomorphine Hydrobromide
CAS No.	85199-01-5
Molecular Formula	C18H22BrNO2
Molecular Weight	364.28 g/mol
Synonyms	(-)-N-n-Propylnorapomorphine Hydrobromide; (R)-(-)-11-Hydroxy-N-propylnoraporphine Hydrobromide; R-(-)-N-Propylnorapomorphine HBr; R(-)-11-Hydroxy-N-propylnoraporphine Hydrobromide; N-Propylnorapomorphine Hydrobromide (R-enantiomer); (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol Hydrobromide, N-Propyl Derivative; APO HBr derivative
EINECS	Contact for details

Quality Control

Our R(-)-n-Propylnorapomorphine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.