Description

7-Amino-4-Carboxymethylcoumarin is a key fluorescent dye intermediate and a versatile building block in organic synthesis. Its value lies in its unique bifunctional structure, combining a reactive amino group with a carboxylic acid moiety, enabling its use in creating advanced fluorescent probes and markers. This compound is essential for manufacturers and researchers in the life sciences, analytical chemistry, and material science sectors who require high-purity, reliable intermediates for diagnostic and sensor applications.

Application

• Fluorescent Probe Synthesis: A critical precursor for developing sensitive fluorescent probes and tags used in bioimaging, immunoassays, and cell biology studies.
• Bioconjugation & Labeling: Used to label proteins, antibodies, and other biomolecules due to its reactive amino and carboxyl groups, facilitating the creation of diagnostic reagents.
• Analytical Chemistry Standards: Serves as a reference standard and intermediate in HPLC and fluorescence-based analytical methods for quality control and research.
• Material Science Research: Employed in the development of novel photoluminescent materials, sensors, and optoelectronic devices.
• Organic Synthesis Building Block: Utilized in synthesizing more complex heterocyclic compounds and pharmaceutical intermediates.

Basic Information

Product Name	7-Amino-4-Carboxymethylcoumarin
CAS No.	85157-21-7
Molecular Formula	C11H9NO4
Molecular Weight	219.19 g/mol
Synonyms	7-Amino-4-(carboxymethyl)-2H-chromen-2-one; ACC; 7-Amino-4-(carboxymethyl)coumarin; 4-Carboxymethyl-7-aminocoumarin; Coumarin 120 acid; 7-Amino-4-(methoxycarbonyl)coumarin (related ester); AMCC; 2-Oxo-2H-chromene-7-amino-4-acetic acid
EINECS	Contact for details

Quality Control

Our 7-Amino-4-Carboxymethylcoumarin is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light, which can affect stability and performance.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.