Description

2',5'-Oligoadenyl-5'-Diphosphate is a biologically significant nucleotide derivative, specifically a 2',5'-linked oligoadenylate with a 5'-diphosphate moiety. This compound is a key intermediate and research tool in the study of the 2-5A synthetase/RNase L pathway, a crucial antiviral and antiproliferative mechanism in mammalian cells. It is essential for researchers and developers in pharmaceutical discovery, biochemistry, and molecular biology who are investigating innate immunity, antiviral drug mechanisms, and cellular signaling pathways.

Application

• Biochemical Research: As a substrate or standard for studying the activity of 2-5A synthetase and RNase L enzymes.
• Antiviral Mechanism Studies: Investigating the 2-5A pathway's role in cellular defense against viral infections.
• Pharmaceutical Development: Serving as a reference compound or intermediate in the development of novel immunomodulatory or antiviral therapeutics.
• Cell Signaling Research: Probing interferon-mediated pathways and their regulation of cell growth and apoptosis.
• Enzyme Kinetics & Assay Development: Used in enzymatic assays to characterize kinetics and inhibition profiles.
• Diagnostic Reagent Component: Potential use in diagnostic kits targeting components of the innate immune response.

Basic Information

Product Name	2',5'-Oligoadenyl-5'-Diphosphate
CAS No.	84824-01-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2',5'-Oligoadenylate 5'-diphosphate; 2-5A Diphosphate; 2',5'-Oligoadenylic Acid 5'-Diphosphate; pppA2'p5'A2'p5'A; 2',5'-Oligo(A) Core with 5'-Diphosphate; 2-5A (5'-diphosphate); Adenosine, 5'-[5'-[5'-(dihydrogen phosphate)oxyphosphinyl]oxyphosphinyl]oxy-2',5'-bis(adenylyl)-; Oligoadenylic acid (2'->5'), 5'-(trihydrogen diphosphate)
EINECS	Contact for details

Quality Control

Our 2',5'-Oligoadenyl-5'-Diphosphate is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for life science research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV spectrophotometry)
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.