Description

5-Pyrimidinecarboxamide, n-((1-Benzyl-2-Pyrrolidinyl)Methyl)-4-Methoxy -2-(Methylamino)-, Dihydrochloride is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) intermediate of significant importance in pharmaceutical research and development. This compound is critical for the synthesis of advanced antiviral agents, offering researchers a reliable building block for creating novel therapeutic candidates. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of non-nucleoside reverse transcriptase inhibitors (NNRTIs) for antiviral therapies.
• Antiviral Drug Research: Used in the discovery and optimization of new chemical entities targeting viruses such as HIV.
• Biochemical Research: Employed as a reference standard or probe in enzymatic studies to understand reverse transcriptase inhibition mechanisms.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for active pharmaceutical ingredients (APIs).
• Academic Research: Supports medicinal chemistry and pharmacology studies in university and institutional laboratories.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, proprietary molecules for client-specific drug discovery projects.

Basic Information

Item	Details
Product Name	5-Pyrimidinecarboxamide, n-((1-Benzyl-2-Pyrrolidinyl)Methyl)-4-Methoxy -2-(Methylamino)-, Dihydrochloride
CAS No.	84332-25-2
Molecular Formula	C19H27N5O2 · 2HCl
Molecular Weight	438.37 g/mol (Free base: 357.45 g/mol)
Synonyms	N-((1-Benzyl-2-pyrrolidinyl)methyl)-4-methoxy-2-(methylamino)-5-pyrimidinecarboxamide dihydrochloride; Delavirdine Dihydrochloride Intermediate; Delavirdine Mesylate Related Compound; U-90152S Dihydrochloride; BHAP Derivative; NNRTI Intermediate; 5-Carboxamide Pyrimidine Derivative; 1-Benzyl-2-((4-methoxy-2-(methylamino)pyrimidine-5-carboxamido)methyl)pyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxamide, n-((1-Benzyl-2-Pyrrolidinyl)Methyl)-4-Methoxy -2-(Methylamino)-, Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.