Description

2,6-Difluoro-3-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and carboxylic acid groups on a difluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates where the difluoro motif can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the nitro and fluorine substituents for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic core.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2,6-Difluoro-3-Nitrobenzoic Acid
CAS No.	83141-10-0
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	3-Nitro-2,6-difluorobenzoic Acid; 2,6-Difluoro-3-nitrobenzoic acid; Benzoic acid, 2,6-difluoro-3-nitro-; 83141-10-0; 2,6-Difluoro-3-nitro-benzoic acid; 2,6-Difluoro-3-nitrobenzoicacid; SCHEMBL233055; DTXSID60674460
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-3-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.