Description

Piroxicillin is a semi-synthetic penicillin derivative, a key intermediate in the synthesis of advanced β-lactam antibiotics. This compound is essential for pharmaceutical manufacturers requiring high-purity building blocks to ensure the efficacy and safety of final drug products. It is primarily utilized by the pharmaceutical industry in the research, development, and production of next-generation antibacterial agents targeting resistant strains.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of advanced penicillin and cephalosporin-class antibiotics.
• Antibacterial Drug Development: Used in R&D for creating new β-lactam antibiotics with improved spectra of activity.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthesis processes for final drug substances.
• Biochemical Research: Employed in studies investigating bacterial resistance mechanisms and the structure-activity relationships of β-lactams.
• Veterinary Medicine: Potential use in the development of antibacterial treatments for animal health.

Basic Information

Product Name	Piroxicillin
CAS No.	82509-56-6
Molecular Formula	C16H18N4O6S2
Molecular Weight	426.47 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-(D-α-Aminophenylacetamido)penicillanic acid; Ampicillin; D-(-)-α-Aminobenzylpenicillin; Binotal; Penbritin; Omnipen; Principen
EINECS	Contact for details

Quality Control

Our Piroxicillin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting full compliance are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.